A vacuole is a bubble of space and time that is separate from the Pattern. Time can run much faster or slower than normal in a vacuole. Vacuoles were studied during the Age of Legends, but were never fully understood. If a vacuole breaks loose, something which can happen randomly, it and its contents are lost forever. (ACoS,Ch25)

References (Possible Spoilers)#

  1. In A Crown of Swords
    1. ACoS,Ch25 - After Moghedien is mindtrapped she is kept in a vacuole by Shaidar Haran.
    2. ACoS,Ch25 - Even Mesaana does not fully understand vacuoles.